Home' Trinidad and Tobago Guardian : August 13th 2015 Contents B50
body & soul
Guardian www.guardian.co.tt Thursday, August 13, 2015
Emerging research suggests the brains of people
with epilepsy appear to react to music differently
from the brains of those who do not have the dis-
Investigators believe this finding could facilitate
the development of new therapies to prevent seizures.
"We believe that music could potentially be used
as an intervention to help people with epilepsy," said
Christine Charyton, PhD, adjunct assistant professor
and visiting assistant professor of neurology at the
Ohio State University Wexner Medical Center.
Charyton presented the research at the American
Psychological Association s 123rd Annual Convention.
Experts explain that approximately 80 per cent of
epilepsy cases are what is known as temporal lobe
epilepsy, in which the seizures appear to originate in
the temporal lobe of the brain.
This same area of the brain is where music is
processed, which was why Charyton wanted to study
the effect of music on the brains of people with
Charyton and her colleagues compared the musical
processing abilities of the brains of people with and
without epilepsy using an electroencephalogram.The
intervention includes the attachment of electrodes
to the scalp whereby they detect and record brain
Investigators collected data from 21 patients who
were in the epilepsy monitoring unit at the Ohio
State University Wexner Medical Center between
September 2012 and May 2014.
The researchers recorded brain wave patterns while
patients listened to ten minutes of silence, followed
by either Mozart s Sonata for Two Pianos in D major"
andante movement (K. 448), or John Coltrane s ren-
dition of My Favourite Things, a second ten-minute
period of silence, the other of the two musical pieces
and finally a third ten-minute period of silence.
The order of the music was randomised, meaning
some participants listened to Mozart first and other
participants listened to Coltrane first.
The researchers found significantly higher levels
of brain wave activity in participants when they were
listening to music. More important, said Charyton,
Brains of epileptics react
differently to music
brain wave activity in people with epilepsy tended
to synchronise more with the music, especially
in the temporal lobe, than in people without
While she does not believe music would replace
current epilepsy therapy, Charyton said this
research suggests music might be a novel inter-
vention used in conjunction with traditional
treatment to help prevent seizures in people with
epilepsy. (American Psychological Association)
Brain wave activity in
people with epilepsy tends
to synchronise more with
the music, especially in the
temporal lobe, than in
people without epilepsy, a
new study finds.
YOUR DAILY HEALTH
News and Advice
The approval of a new 3D-printed epilepsy drug
in the US could have potentially significant impli-
cations for the future treatment of not only epilepsy,
but a host of other conditions.
Manufacturer Aprecia Pharmaceuticals has secured
US Food and Drug Administration approval for Spri-
tam levetiracetam, an oral prescription adjunctive
therapy for the treatment of partial onset seizures,
myoclonic seizures and primary generalised tonic-
clonic seizures in adults and children with epilepsy.
The significance of the drug comes from the fact
it has been developed using ZipDose Technology,
allowing 3D printing to be used to produce a porous
formulation that rapidly disintegrates with only a
small sip of liquid. This enables the delivery of a
high drug load---up to 1,000 mg in a single dose---
in a format that is extremely easy for the patient to
administer. In addition, the fact that each dose is
individually packaged means no measuring is required,
making the treatment extremely portable.
It is thought that the development and planned
launch of this therapy early next year will prove ben-
eficial in combating the problem of non-compliance
with prescribed epilepsy treatment regimens, which
is a key reason for the failure of many courses of
drug receives US approval
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