Home' Trinidad and Tobago Guardian : November 9th 2015 Contents A28
body & soul
Guardian www.guardian.co.tt Monday, November 9, 2015
23rd and 24th November, 2015
26th & 27th November, 2015
Hyatt Trinidad Hotel, Wrightson Road, Port-of-Spain
David Heslett, Bsc (Hon), CEng, FICE, Managing Director-ECV
For further info: 623-9396 or 627-2522 or 720-0850 Fax: 625-5749
Email: firstname.lastname@example.org or website: jcc.org.tt
WHO SHOULD ATTEND?
The seminar provides the necessary knowledge for professionals from Government Ministries and
Agencies, Private Sector Employers, Consulting Engineers, Contractors, Quantity Surveyors, Architects,
Legal Advisers, Project and Construction Managers and all involved with the implementation and
management of large Works Contracts and the next generation of International Projects. It is particularly
important to those involved in preparing or managing infrastructure projects.
These courses are designed for optimum interaction to help participants have confidence in working with
these documents whether representing Employers, Consultants or Contractors and provide professionals
with essential contractual know-how for working on future international projects.
Contract documents & awards, contract startup,
post commencement date administration, financial
controls & disciplines, claims, suspension & termi-
nation, disputes, amicable settlement & arbitration,
taking over the works & defects notification period
& contract completion, differences between FIDIC
& MDB'S Harmonised Construction Contract.
Project risks & causes of claims, claims and
contractual procedures, time related entitlements,
additional payment, claims, establishment of
disputes adjudication board (DAB), DAB
procedural rules (PR), DAB decision, engineer as
DAB amicable settlement & arbitration
While he couldn t possibly have known, Sandy
Halperin was likely around 35 years old when
his brain began slowly accumulating the plaques
and tangles of Alzheimer s disease.
Thanks to recent advances that allow us to see
disease in the living brain, we now know there is
evidence of Alzheimer's in neural tissue 20 to 30
years before one first starts noticing lapses in
memory. By age 60, when Sandy first started losing
words and forgetting his intentions, the disease
was already advanced, even if Sandy and his family
were noticing symptoms for the first time.
According to Harvard's Rudy Tanzi, when brain
cells, known as glia, sense the death of other brain
cells from plaques and tangles, they assume one
In an attempt to fight these "foreign invaders"
the brain becomes flooded with inflammatory free
radicals that begin a vicious war inside the brain.
But the infection doesn't actually exist; the brain
is fighting a ghost.
Over the last three
years, we have fre-
quently visited with
Sandy as he slowly
aren't many happy
endings with stories
disease, but Sandy's
story is different
He wants to open
up his life and his
brain to us, and to
science. He wants to
advances taking place
in Alzheimer's, even
if he is not around to
benefit from them.
Alzheimer's disease remains the only leading
cause of death that is not currently preventable,
let alone curable. Most existing treatments revolve
around keeping certain neurotransmitters, such
as acetylcholine, around in the brain longer after
Alzheimer's has already taken hold. But that is
like bringing a knife to a gun fight.
Still, there is remarkable enthusiasm today from
scientists. Tanzi's group has created an
"Alzheimer's-in-a-dish" model. It is essentially
mini brains created with human nerve cells grown
in a petri dish.
This allows Alzheimer's disease to be studied
like never before. From this and other models, we
have learned, for example, that it is the beta-amy-
loid plaques that come first---and early. The tangles
caused by tau only occur much later, closer to the
beginning of symptoms. So if we can reduce early
plaque formation with a sort of vaccine, the word
"cure" starts getting tossed around by normally
"This is an exciting time," the Alzheimer's Asso-
ciation's Dean Hartley told me as he looks to the
future. "If most people start symptoms at 65, then
we might extrapolate and say we need to be treating
a beta-amyloid checkup to see if you need some
type of treatment or intervention." (CNN)
Competition between different
bacteria species in the gut is what
keeps humans healthy, a study
The research, published in the
journal Science, uses mathematical
theory to suggest how microbes
in the gut maintain stability.
Scientists previously thought
bacteria were co-operating, but
the Oxford University study sug-
gests competition between them
makes for good health.
Prof Kevin Foster said bacteria
acted like "trees competing in a
"The assumption has always
been that because these bacteria
are doing us good, the commu-
nities must be co-operating with
The study suggested if bacteria
were co-operating, it could actu-
ally destabilise the body's systems
and lead to poor health.
Study: Competing bacteria
in gut makes for good health
We now know there is evidence of Alzheimer's in neural tissue
20 to 30 years before one first starts noticing lapses in memory.
YOUR DAILY HEALTH
News and Advice
remains the only
leading cause of death
that is not currently
preventable, let alone
curable. Most existing
around keeping certain
such as acetylcholine,
around in the brain
already taken hold. But
that is like bringing a
knife to a gun fight.
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