Home' Trinidad and Tobago Guardian : October 8th 2013 Contents A32
body & soul
Guardian www.guardian.co.tt Tuesday, October 8, 2013
Invitation for Bids (IFB)
ST. VINCENT AND THE GRENADINES
REGIONAL DISASTER VULNERABILITY REDUCTION PROJECT
Credit No.: 4986-VC, CFC-PPCR Grant No. TF010206, SCF Loan No.
TF010207, Project ID No.: P117871
St. Vincent and the Grenadines has received financing from the International Bank
for Reconstruction and Development (The World Bank) toward the cost of the
Regional Disaster Vulnerability Reduction Project, and it intends to apply part of
the proceeds of this credit to payments under the Contract for the Procurement of
Equipment for Satellite Warehouses:
SVGRDVRP-G-ICB-7- Equipment for Satellite Warehouses
Lot 1: Personal Protective, Communications & Security Equipment
Lot 2: Stretchers & Cots
Lot 3: Water and Sanitation
Lot 4: Hand Tools
Lot 5: Power Tools and Equipment
Lot 6: Lighting
Lot 7: Tarpaulins and Rope
Lot 8: Medical Supplies
Lot 9: Safety Equipment: Fire fighting
Lot 10: Relief Shelter Equipment: Kitchen
The Central Planning Division now invites sealed bids from eligible and qualified bidders on a lots
basis. The delivery period is 90 days. Bidders may obtain further information via the Invitation to
Tender link in the Web Classifieds section at www.gov.vc or at the address below during office
hours 8:00 am to 4:00 pm:
Hold your nose and don t spit out your coffee:
Doctors have found a way to put healthy people s
poop into pills that can cure serious gut infections
---a less yucky way to do "fecal transplants." Canadian
researchers tried this on 27 patients and cured them
all after strong antibiotics failed to help.
It s a gross topic but a serious problem. Half a million
Americans get Clostridium difficile, or C-diff, infections
each year, and about 14,000 die. The germ causes
nausea, cramping and diarrhea so bad it is often dis-
abling. A very potent and pricey antibiotic can kill C-
diff but also destroys good bacteria that live in the gut,
leaving it more susceptible to future infections.
Recently, studies have shown that fecal transplants
---giving infected people stool from a healthy donor---
can restore that balance. But they re given through
expensive, invasive procedures like colonoscopies or
throat tubes. Doctors also have tried giving the stool
through enemas but the treatment doesn t always take
There are even YouTube videos on how to do a similar
treatment at home via an enema. A study in a medical
journal of a small number of these "do-it-yourself"
cases suggests the approach is safe and effective.
Dr Thomas Louie, an infectious disease specialist
at the University of Calgary, devised a better way--- a
one-time treatment custom-made for each patient.
Donor stool, usually from a relative, is processed in
the lab to take out food and extract the bacteria and
clean it. It is packed into triple-coated gel capsules so
they won t dissolve until they reach the intestines.
"There s no stool left---just stool bugs. These people
are not eating poop," and there are no smelly burps
because the contents aren t released until they re well
past the stomach, Louie said.
Days before starting the treatment, patients are given
an antibiotic to kill the C-diff. On the morning of the
treatment, they have an enema so "the new bacteria
coming in have a clean slate," Louie said.
It takes 24 to 34 capsules to fit the bacteria needed
for a treatment, and patients down them in one sitting.
The pills make their way to the colon and seed it with
the normal variety of bacteria.
Louie described 27 patients treated this way on
October 3 at IDWeek, an infectious diseases conference
in San Francisco. All had suffered at least four C-diff
infections and relapses, but none had a recurrence
after taking the poop pills.
Margaret Corbin, 69, a retired nurse s aide from
Calgary, told of the misery of C-diff.
"It lasted for two years. It was horrible. I thought
I was dying. I couldn t eat. Every time I ate anything
or drank water I was into the bathroom," she said. "I
never went anywhere, I stayed home all the time."
With her daughter as the donor, she took pills made
by Louie two years ago, and "I ve been perfectly fine
since," Corbin said.
Dr Curtis Donskey of the Cleveland Veterans Affairs
Medical Center, who has done fecal transplants through
colonoscopies, praised the work.
"The approach that Dr Louie has is completely novel---
no one else has done this," he said. "I am optimistic
that this type of preparation will make these procedures
much easier for patients and for physicians."
The treatment now must be made fresh for each
patient so the pills don t start to dissolve at room tem-
perature, because their water content would break down
the gel coating. Minnesota doctors are testing freezing
stool, which doesn t kill the bacteria, so it could be
stored and shipped anywhere a patient needed it.
"You could have a universal donor in Minnesota
provide a transplant for someone in Florida. That s
where we re heading," Donskey said.
Other researchers are trying to find which bacteria
most help fight off C-diff. Those might be grown in
a lab dish and given to patients rather than the whole
spectrum of bacteria in stool.
The hope is "we could administer that as a probiotic
in a pill form," Donskey said.
Louie sees potential for the poop pills for other
people with out-of-whack gut bacteria, such as hos-
pitalised patients vulnerable to antibiotic-resistant
"This approach, to me, has wide application in med-
icine," he said. "So it s not just about C-diff." (AP)
Pills made from poop cure
serious gut infections
YOUR DAILY HEALTH
News and advice
Dr Thomas Louie, an infectious disease specialist
at the University of Calgary, holds a container of
stool pills in triple-coated gel capsules in his lab in
Calgary, Alberta, Canada. AP PHOTO
Links Archive October 7th 2013 October 9th 2013 Navigation Previous Page Next Page